Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxycinnamic Acid SCHEMBL14874574 | 0.88 | THRB (0.57) | THRBATMPPARAFFAR1PPARG | |
| 4-Methoxycinnamic Acid SCHEMBL19717858 | 0.88 | LMNA (0.62) | THRBATMTAS1R3TAS1R1TDP1 | |
| 4-Methoxycinnamic Acid SCHEMBL5669618 | 0.86 | THRB (0.68) | THRBATMPPARAFFAR1PPARG | |
| Monoctanoin Component A SCHEMBL392377 | 0.85 | KDM4E (0.58) | THRBATMNPC1RAB9ATAS1R3 | |
| SCHEMBL7273131 | 0.83 | TP53 (0.60) | THRBATM | |
| SCHEMBL14566051 | 0.83 | DGKA (0.59) | THRBDGKA | |
| SCHEMBL7242747 | 0.83 | TP53 (0.60) | THRBATM | |
| SCHEMBL7273143 | 0.83 | TP53 (0.60) | THRBATM | |
| SCHEMBL9650506 | 0.83 | TP53 (0.60) | THRBATM | |
| SCHEMBL7044767 | 0.83 | TP53 (0.60) | THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124490-A | REACTING A DIAMINO-CONTAINING POLYSILOXANE WITH AN UNSATURATED DICARBOXYLIC ACID OR CYCLIC ANHYDRIDE IN THE PRESENCE OF A LOW MOLECULAR WEIGHT SILICONE OIL OR OTHER SOLVENT TO FORM A GEL | MONA INDUSTRIES, INC. (US) | 2000-09-26 | — | — | US | disclosed |