Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083456 | 0.83 | MMP8 (0.46) | SPHK1MMP8 | |
| SCHEMBL8083610 | 0.83 | MMP8 (0.54) | CYP2C9CYP2C19SPHK1MMP8POLB | |
| SCHEMBL8089921 | 0.83 | MMP8 (0.48) | CYP3A4CYP2C19SPHK1MMP8 | |
| SCHEMBL7438577 | 0.82 | TACR3 (0.31) | ALDH1A1CYP3A4CYP2C9CYP2C19TACR3 | |
| SCHEMBL8083488 | 0.82 | MMP8 (0.45) | SPHK1MMP8 | |
| SCHEMBL7433844 | 0.81 | F2 (0.37) | ALDH1A1 | |
| SCHEMBL8083554 | 0.81 | MMP8 (0.46) | SPHK1MMP8SMN1; SMN2 | |
| SCHEMBL7438262 | 0.79 | CYP3A4 (0.51) | ALDH1A1CYP3A4CYP2C9CYP2C19MMP8 | |
| SCHEMBL8095062 | 0.78 | MMP8 (0.48) | SPHK1MMP8SMN1; SMN2 | |
| SCHEMBL8083629 | 0.77 | KDM1A (0.40) | SPHK1MMP8HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |