Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079639 | 0.75 | ALDH1A1 (0.70) | ALDH1A1ENPP3ENPP1 | |
| SCHEMBL21878824 | 0.73 | USP30 (1.00) | USP30 | |
| SCHEMBL21878826 | 0.73 | USP30 (1.00) | USP30 | |
| SCHEMBL9057935 | 0.73 | RECQL (0.94) | RECQLLMNAPOLBTP53ALDH1A1 | |
| SCHEMBL7436989 | 0.73 | ADAMTS4 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL517633 | 0.72 | RECQL (0.91) | RECQLLMNAPOLBTP53ALDH1A1 | |
| SCHEMBL21444578 | 0.72 | RECQL (0.91) | RECQLLMNAPOLBTP53ALDH1A1 | |
| SCHEMBL9927461 | 0.72 | RECQL (0.91) | RECQLLMNAPOLBTP53ALDH1A1 | |
| SCHEMBL12376703 | 0.71 | TP53 (0.79) | TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL945862 | 0.71 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |