Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337317 | 0.95 | GAA (0.36) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8098249 | 0.95 | CYP1A2 (0.33) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL7848364 | 0.89 | SMN1; SMN2 (0.32) | GAACYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL8013343 | 0.82 | GAA (0.38) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8099222 | 0.82 | GAA (0.38) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8649980 | 0.80 | GABRA2 (0.45) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8098047 | 0.80 | GAA (0.36) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8100183 | 0.80 | GAA (0.36) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8013354 | 0.79 | GAA (0.36) | GAACYP1A2GABRA2GABRB2GABRA1 | |
| SCHEMBL8011792 | 0.79 | GAA (0.36) | GAACYP1A2GABRA2GABRB2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057454-A | USEFUL FOR TREATING OR PREVENTING ALL ISCHAEMIAS (SUCH AS FOCAL OR GLOBAL ISCHAEMIA) RESULTING FROM CEREBROVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2000-05-02 | — | — | US | disclosed |