Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098246 | 0.95 | GAA (0.38) | CYP1A2ALDH1A1GAAGABRA1GABRG2 | |
| SCHEMBL7848364 | 0.95 | SMN1; SMN2 (0.32) | CYP1A2SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL8337317 | 0.93 | GAA (0.36) | CYP1A2SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL8316162 | 0.81 | MAPT (0.41) | CYP1A2SMN1; SMN2ALDH1A1LMNAGABRA1 | |
| SCHEMBL8098049 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1LMNAGAAGABRA1 | |
| SCHEMBL8100190 | 0.81 | SMN1; SMN2 (0.33) | CYP1A2SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL8011799 | 0.80 | CYP1A2 (0.32) | CYP1A2SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL8013343 | 0.79 | GAA (0.38) | CYP1A2SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL7835755 | 0.77 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL8099222 | 0.77 | GAA (0.38) | CYP1A2ALDH1A1GAAGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057454-A | USEFUL FOR TREATING OR PREVENTING ALL ISCHAEMIAS (SUCH AS FOCAL OR GLOBAL ISCHAEMIA) RESULTING FROM CEREBROVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2000-05-02 | — | — | US | disclosed |
| US-5902803-A | 5H,10H-imidazo 1,2-a!indeno 1,2-e!pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE-POULENC RORER S.A. (FR) | 1999-05-11 | — | — | US | disclosed |