Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | SRC | P12931 | 7/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948504 | 0.85 | ABCB1 (0.38) | ABCB1IDO1SRCPARP1UCHL1 | |
| SCHEMBL21286395 | 0.85 | ABCB1 (0.38) | ABCB1IDO1SRCPARP1UCHL1 | |
| SCHEMBL29985450 | 0.85 | ABCB1 (0.38) | ABCB1IDO1SRCPARP1UCHL1 | |
| SCHEMBL1526220 | 0.83 | ABCB1 (0.37) | ABCB1IDO1SRCPARP1UCHL1 | |
| SCHEMBL1526218 | 0.83 | ABCB1 (0.37) | ABCB1IDO1SRCPARP1UCHL1 | |
| SCHEMBL8106554 | 0.81 | ABCB1 (0.35) | ABCB1IDO1SRCPARP1HTRA1 | |
| SCHEMBL9595418 | 0.81 | ABCB1 (0.35) | ABCB1IDO1SRCPARP1HTRA1 | |
| SCHEMBL7859886 | 0.78 | NR1H2 (0.46) | ABCB1SRCPARP1UCHL1KLK7 | |
| SCHEMBL8107520 | 0.78 | NR1H2 (0.34) | ABCB1SRC | |
| SCHEMBL3948290 | 0.77 | ABCB1 (0.41) | ABCB1SRCPARP1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |