Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.45 |
| ▸ | FNTB | P49356 | 12/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ERG | P11308 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097930 | 0.92 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8095888 | 0.85 | FNTA (0.42) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8437320 | 0.84 | GPBAR1 (0.52) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8098513 | 0.84 | GPBAR1 (0.52) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8103795 | 0.83 | CYP11B1 (0.41) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8097850 | 0.82 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8088935 | 0.82 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8095903 | 0.82 | CYP11B1 (0.45) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8098226 | 0.82 | FNTA (0.45) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8097915 | 0.82 | FNTA (0.45) | FNTAFNTBCYP11B1CYP11B2PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |