Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.56 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993505 | 0.98 | L3MBTL1 (0.58) | L3MBTL1LTB4RLTB4R2PLAAT3PLAAT5 | |
| SCHEMBL28901341 | 0.89 | L3MBTL1 (0.57) | L3MBTL1LTB4RLTB4R2PLAAT3PLAAT5 | |
| SCHEMBL4149143 | 0.83 | L3MBTL1 (0.55) | L3MBTL1LTB4RLTB4R2ALOX5SMPD1 | |
| SCHEMBL8084814 | 0.80 | ALOX5 (0.58) | L3MBTL1LTB4RLTB4R2ALOX5ALDH1A1 | |
| SCHEMBL10452641 | 0.79 | PDE4D (0.54) | L3MBTL1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL706154 | 0.79 | LPAR1 (0.78) | L3MBTL1LTB4R2LPAR1 | |
| SCHEMBL12971411 | 0.78 | EBP (0.68) | PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL10526510 | 0.78 | EBP (0.68) | PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL4693129 | 0.77 | CYP1A2 (0.54) | L3MBTL1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5209919 | 0.77 | KMT2A (0.52) | L3MBTL1LTB4RLTB4R2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136819-A | COMPOUNDS FOR ANTIINFLAMMATORY AGENTS OR CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM GMBH (DE) | 2000-10-24 | — | — | US | disclosed |
| US-5968948-A | FOR TREATMENT OF EPILEPSY, STROKE, ALZHEIMER'S DISEASE, BRAIN DISEASES OR AS ANTIINFLAMMATORY OR ANTIPROLIFERATIVE AGENTS | BOERHINGER INGELHEIM GMBH (DE) | 1999-10-19 | — | — | US | disclosed |
| US-5661157-A | Annelated dihydropyridines and the use thereof for preparing pharmaceutical preparations | BOEHRINGER INGELHEIM KG (DE) | 1997-08-26 | — | — | US | disclosed |