Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690968 | 0.88 | KDM4E (0.55) | CYP1A2CYP3A4CYP2D6L3MBTL1BLM | |
| SCHEMBL5464537 | 0.84 | CYP3A4 (0.48) | CYP1A2CYP3A4CYP2D6L3MBTL1BLM | |
| SCHEMBL81112 | 0.81 | KDM4E (0.63) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL7266646 | 0.80 | CYP3A4 (0.79) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL4860600 | 0.79 | KDM4E (0.61) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL901495 | 0.79 | L3MBTL1 (0.54) | CYP1A2CYP3A4CYP2D6L3MBTL1BLM | |
| SCHEMBL7156624 | 0.79 | PLAAT3 (0.56) | KDM4EPOLBLDHAPLAAT3PLAAT5 | |
| SCHEMBL5464541 | 0.79 | ALDH1A1 (0.49) | CYP1A2CYP3A4CYP2D6L3MBTL1BLM | |
| SCHEMBL4694221 | 0.78 | AOC3 (0.43) | CYP1A2CYP3A4CYP2D6L3MBTL1BLM | |
| SCHEMBL9506664 | 0.78 | KDM4E (0.59) | CYP1A2CYP3A4CYP2D6BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682547-B1 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM CA LTD (CA) | 2012-10-24 | — | — | EP | disclosed |
| EP-1682547-A4 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM CA LTD (CA) | 2008-12-31 | — | — | EP | disclosed |
| US-7323567-B2 | RSV polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2008-01-29 | — | — | US | disclosed |
| EP-1682547-A1 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2006-07-26 | — | — | EP | disclosed |
| US-20050239814-A1 | RSV polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2005-10-27 | — | — | US | disclosed |
| WO-2005042530-A1 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239814-A1 | RSV polymerase inhibitors | POLR2E, POLR2H, POLR2A | CYP1A2 3056/4885CYP3A4 2628/4885CYP2D6 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.