Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6148751 | 0.81 | KMT2A (0.63) | ADRB2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL27535388 | 0.81 | KMT2A (0.63) | ADRB2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8428854 | 0.80 | ALDH1A1 (0.61) | ADRB2KMT2AALDH1A1MEN1PLAAT3 | |
| SCHEMBL29672138 | 0.80 | HAT1 (0.77) | — | |
| SCHEMBL14831778 | 0.80 | HAT1 (0.77) | — | |
| SCHEMBL742343 | 0.80 | KMT2A (0.71) | ADRB2KMT2AALDH1A1MEN1PLAAT3 | |
| SCHEMBL2778736 | 0.79 | ALDH1A1 (0.57) | ADRB2KMT2AALDH1A1MEN1PLAAT3 | |
| SCHEMBL11341183 | 0.79 | ULK1 (0.52) | KMT2AMEN1CA12CA2CA9 | |
| SCHEMBL11341169 | 0.79 | ULK1 (0.52) | KMT2AMEN1CA12CA2CA9 | |
| SCHEMBL8098635 | 0.79 | ALDH1A1 (0.62) | ADRB2KMT2AALDH1A1MEN1PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136819-A | COMPOUNDS FOR ANTIINFLAMMATORY AGENTS OR CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM GMBH (DE) | 2000-10-24 | — | — | US | disclosed |
| US-5968948-A | FOR TREATMENT OF EPILEPSY, STROKE, ALZHEIMER'S DISEASE, BRAIN DISEASES OR AS ANTIINFLAMMATORY OR ANTIPROLIFERATIVE AGENTS | BOERHINGER INGELHEIM GMBH (DE) | 1999-10-19 | — | — | US | disclosed |
| US-5661157-A | Annelated dihydropyridines and the use thereof for preparing pharmaceutical preparations | BOEHRINGER INGELHEIM KG (DE) | 1997-08-26 | — | — | US | disclosed |