⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538164 | 0.84 | — | — | |
| SCHEMBL2344465 | 0.78 | MAPK1 (0.37) | — | |
| SCHEMBL9229585 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL11542686 | 0.73 | CA1 (0.46) | — | |
| SCHEMBL11509114 | 0.71 | CYP3A4 (0.42) | — | |
| SCHEMBL11673433 | 0.70 | TRPA1 (0.34) | — | |
| SCHEMBL5962213 | 0.69 | CYP2A6 (0.39) | — | |
| SCHEMBL11508298 | 0.69 | HSP90AA1 (0.37) | — | |
| SCHEMBL8384 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL1224689 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| US-4289720-A | POLYSILOXANE ADDITIVE | THE FOUNDATION: THE RESEARCH INSTITUTE FOR SPECIAL INORGANIC MATERIALS (JP) | 1981-09-15 | — | — | US | disclosed |