Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590537 | 1.00 | S100B (0.51) | S100BCNR2KDM4EALDH1A1HPGD | |
| SCHEMBL8593537 | 0.97 | S100B (0.50) | S100BCNR2KDM4EALDH1A1HPGD | |
| SCHEMBL10573626 | 0.93 | S100B (0.54) | S100BCNR2KDM4EALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL8822541 | 0.89 | S100B (0.60) | S100BKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8011679 | 0.88 | S100B (0.48) | S100BCNR2KDM4EALDH1A1HPGD | |
| SCHEMBL8633133 | 0.87 | CNR2 (0.40) | S100BCNR2KDM4EALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL8647343 | 0.86 | S100B (0.59) | S100BCNR2KDM4EALDH1A1HPGD | |
| SCHEMBL2137159 | 0.85 | S100B (0.50) | S100BCNR2ALDH1A1MAPTHTT | |
| SCHEMBL7719548 | 0.85 | S100B (0.50) | S100BCNR2ALDH1A1MAPTHTT | |
| SCHEMBL1537895 | 0.85 | S100B (0.70) | S100BKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568777-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1993-11-10 | — | — | EP | claimed |
| EP-0553622-B1 | Silver halide photographic light-sensitive material | KONISHIROKU PHOTO IND (JP) | 2000-12-13 | — | — | EP | disclosed |
| US-5576161-A | POLYHYDRIC ALCOHOL | KONICA CORPORATION (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0697625-A2 | Silver halide light-sensitive photographic material and method of processing thereof | KONICA CORPORATION (JP) | 1996-02-21 | — | — | EP | disclosed |
| EP-0554027-B1 | Silver halide photographic light sensitive material and its processing method | KONISHIROKU PHOTO IND (JP) | 1995-12-20 | — | — | EP | disclosed |
| US-5362626-A | Support, silver chlorobromide emulsion layer with grains at least 95 mol % silver chloride, gelatin with 0.5-5 ppm iron ion and at least 40 % by weight of alpha-constituent having weight-average molecular weight of 80,000-120,000 | KONICA CORPORATION (JP) | 1994-11-08 | — | — | US | disclosed |
| US-5356760-A | Silver chlorobromide emulsion containing resorcinol-based or aminophenol-based coupler, gelatin in specifed coating weight, on support | KONICA CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0593180-A1 | A silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |
| EP-0568777-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |
| EP-0553622-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0554027-A1 | Silver halide photographic light sensitive material and its processing method | KONICA CORPORATION (JP) | 1993-08-04 | — | — | EP | disclosed |