Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593537 | 0.90 | S100B (0.50) | CNR2S100BKDM4EALDH1A1GAA | |
| SCHEMBL8098717 | 0.87 | S100B (0.51) | CNR2S100BKDM4EALDH1A1GAA | |
| SCHEMBL8590537 | 0.87 | S100B (0.51) | CNR2S100BKDM4EALDH1A1GAA | |
| SCHEMBL5491814 | 0.82 | S100B (0.46) | S100BKDM4EALDH1A1GAAMAPT | |
| SCHEMBL10573626 | 0.82 | S100B (0.54) | CNR2S100BKDM4EALDH1A1GAA | |
| Sulfuric Acid SCHEMBL8050521 | 0.80 | S100B (0.44) | S100BKDM4EALDH1A1GAAMAPT | |
| Sulfuric Acid SCHEMBL10709596 | 0.80 | S100B (0.44) | S100BKDM4EALDH1A1GAAMAPT | |
| Sulfuric Acid SCHEMBL8647343 | 0.79 | S100B (0.59) | CNR2S100BKDM4EALDH1A1MAPT | |
| SCHEMBL8373940 | 0.79 | S100B (0.47) | CNR2S100BKDM4EALDH1A1GAA | |
| SCHEMBL8061571 | 0.77 | S100B (0.49) | S100BKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565023-B1 | Method for processing silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| EP-0565023-A1 | Method for processing silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |