Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | IDH2 | P48735 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16241281 | 0.87 | KIF11 (0.51) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL11114461 | 0.85 | MAPT (0.51) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL10738876 | 0.81 | YAP1 (0.51) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL20714773 | 0.81 | MAPT (0.49) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL15203805 | 0.81 | TAAR1 (0.53) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL8102983 | 0.81 | MAPT (0.53) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL6232265 | 0.81 | LMNA (0.63) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL11115754 | 0.80 | MAPT (0.61) | MAPTGAAALDH1A1NPSR1TDP1 | |
| Hydrochloric Acid SCHEMBL10740311 | 0.80 | YAP1 (0.50) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL11118351 | 0.80 | MAPT (0.51) | MAPTGAAALDH1A1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |