SCHEMBL8098936

SCHEMBL8098936

N[C@@H](CSc1ccccc1)C(=O)OC(=O)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
MTNR1A P48039 3/20 0.42
MTNR1B P49286 3/20 0.42
CA2 P00918 1/20 0.42
CDC25B P30305 1/20 0.42
KMT2A Q03164 3/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 2/20 0.41
GPR55 Q9Y2T6 1/20 0.41
SLC15A1 P46059 1/20 0.41
CASP1 P29466 1/20 0.40
EGFR P00533 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6840772 0.88 ALDH1A1 (0.47) ALDH1A1MAOAMAOBMTNR1AMTNR1B
SCHEMBL19331556 0.85 ALDH1A1 (0.47) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
SCHEMBL11218951 0.84 PPARA (0.46) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
SCHEMBL7272552 0.82 ALDH1A1 (0.47) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
SCHEMBL383649 0.82 ALDH1A1 (0.47) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
SCHEMBL3985411 0.82 SLC7A5 (0.56) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
SCHEMBL11140649 0.81 ALDH1A1 (0.44) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
Hydrochloric Acid SCHEMBL382326 0.81 ALDH1A1 (0.46) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2
SCHEMBL27794910 0.81 ALDH1A1 (0.50) ALDH1A1CA2KMT2AMAPK1L3MBTL1
SCHEMBL6874313 0.79 SLC15A1 (0.49) ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11335351-A None JP disclosed
JP-10029973-A None JP disclosed
JP-2000044522-A FIXATION OF N-PROTECTING GROUP AMINO ACID ESTER MITSUI CHEMICALS INC 2000-02-15 JP disclosed
JP-H11335351-A PURIFICATION OF N-CARBOBENZOXY-S-PHENYLCYSTEINE KANEGAFUCHI CHEM IND CO LTD 1999-12-07 JP disclosed
JP-H1029973-A SEPARATION OF N-CARBOBENZOXY-S-PHENYLCYSTEINE MITSUI PETROCHEM IND LTD 1998-02-03 JP disclosed