Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098936 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL19331556 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL16200533 | 0.84 | IDO1 (0.49) | PPARAPPARGIDO1METAP2 | |
| SCHEMBL10618748 | 0.84 | PPARG (0.49) | PPARAPPARGIDO1METAP2 | |
| SCHEMBL10937504 | 0.83 | METAP2 (0.44) | IDO1METAP2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1927887 | 0.82 | ACE (0.46) | IDO1METAP2 | |
| SCHEMBL11880813 | 0.82 | IDO1 (0.45) | PPARAPPARGIDO1METAP2L3MBTL1 | |
| SCHEMBL3985411 | 0.81 | SLC7A5 (0.56) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL383649 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL7272552 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57183781-A | — | — | None | — | — | JP | disclosed |
| JP-S57183781-A | 7-(S-BENZYL-CYSTENYL)-4-METHYLCOUMARINYL AMIDE AND DETERMINATION OF CYSTINE AMINOPEPTIDASE ACTIVITY USING THE SAME | DAI ICHI PURE CHEM CO LTD | 1982-11-12 | — | — | JP | disclosed |