Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090559 | 0.91 | DRD2 (0.55) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL3563541 | 0.79 | DRD2 (0.55) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL10965901 | 0.79 | DRD2 (0.57) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL3551137 | 0.77 | DRD2 (0.53) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL432973 | 0.76 | ALOX5 (0.55) | DRD2DRD3KCNH2ALOX5ALDH1A1 | |
| SCHEMBL6434435 | 0.76 | CYP17A1 (0.53) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL9819261 | 0.75 | DRD2 (0.54) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL5500122 | 0.75 | DRD2 (0.51) | DRD2DRD3KCNH2CYP17A1ALOX5 | |
| SCHEMBL3561479 | 0.75 | DRD2 (0.48) | DRD2DRD3KCNH2CYP17A1MAPT | |
| SCHEMBL7607804 | 0.75 | CA12 (0.55) | DRD2DRD3KCNH2CYP17A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |