Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281751 | 0.87 | DRD2 (0.52) | DRD2DRD3KCNH2CYP17A1KDM4E | |
| SCHEMBL432973 | 0.85 | ALOX5 (0.55) | DRD2DRD3KCNH2KDM4EALDH1A1 | |
| SCHEMBL9819249 | 0.84 | NOX4 (0.46) | — | |
| SCHEMBL4430571 | 0.81 | MAPT (0.48) | DRD2DRD3KCNH2KDM4EALDH1A1 | |
| SCHEMBL9819448 | 0.80 | DRD2 (0.52) | DRD2DRD3KCNH2ALDH1A1MAPT | |
| SCHEMBL25575682 | 0.80 | L3MBTL1 (0.54) | DRD2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL15837517 | 0.77 | MEN1 (0.62) | DRD2DRD3ALDH1A1ALOX5MEN1 | |
| SCHEMBL6418503 | 0.77 | MEN1 (0.59) | DRD2DRD3ALDH1A1MAPTMEN1 | |
| SCHEMBL5113275 | 0.77 | ALOX5 (0.59) | DRD2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL8098411 | 0.75 | ALOX5 (0.55) | DRD2DRD3KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |