Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794050 | 0.87 | HCAR3 (0.56) | ALDH1A1HPGDMAPTTSHRKMT2A | |
| SCHEMBL30037363 | 0.82 | MAPT (0.63) | ALDH1A1HPGDNPSR1MAPTCYP3A4 | |
| SCHEMBL3546502 | 0.82 | MAPT (0.63) | ALDH1A1HPGDNPSR1MAPTCYP3A4 | |
| SCHEMBL4641784 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL21385340 | 0.82 | MAPT (0.58) | ALDH1A1HPGDMAPTTDP1TSHR | |
| SCHEMBL29594225 | 0.82 | MAPT (0.58) | ALDH1A1HPGDMAPTTDP1TSHR | |
| SCHEMBL4641775 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL7566531 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL30445111 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL1534102 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030952-A | AS HUMAN AND VETERINARY MEDICINE, PARTICULARLY IN THE TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR AND OPHTHALMOLOGIC CONDITIONS, AND IN COSMETIC COMPOSITIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES GALDERMA (FR) | 2000-02-29 | — | — | US | disclosed |