Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097654 | 0.84 | ALOX15 (0.43) | TP53HTTTSHRCTSGCMA1 | |
| SCHEMBL8103224 | 0.82 | MEN1 (0.44) | TSHRRAB9ANPC1POLBKMT2A | |
| SCHEMBL8089858 | 0.82 | POLB (0.44) | RAB9ANPC1PKMPOLBKMT2A | |
| SCHEMBL8097791 | 0.81 | L3MBTL1 (0.45) | HTTKMT2AALDH1A1 | |
| SCHEMBL8097872 | 0.79 | HTT (0.42) | TP53HTTTSHRF2ELANE | |
| SCHEMBL10725840 | 0.79 | ALDH1A1 (0.47) | TP53TSHRCMA1POLBKMT2A | |
| SCHEMBL8098667 | 0.79 | HDAC1 (0.38) | — | |
| SCHEMBL10874381 | 0.77 | IDO1 (0.52) | HTTTSHRPKMPOLBKMT2A | |
| SCHEMBL10733179 | 0.77 | SLC6A2 (0.46) | CTSGCMA1KMT2AALOX12 | |
| SCHEMBL8105245 | 0.73 | ALDH1A1 (0.47) | TSHRCTSGCMA1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |