Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 1/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113217 | 0.88 | MAPT (0.45) | ELANEALDH1A1KDM4EHPGDHTT | |
| SCHEMBL8108281 | 0.87 | NR3C2 (0.42) | ALDH1A1KDM4EHPGDHTTMEN1 | |
| SCHEMBL8115267 | 0.86 | SLC11A2 (0.39) | ALDH1A1KDM4EHPGDHTTMEN1 | |
| SCHEMBL8114850 | 0.84 | HRH2 (0.39) | SLC34A1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8113306 | 0.84 | ALDH1A1 (0.42) | SLC34A1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8108274 | 0.82 | KIF11 (0.41) | SLC34A1ELANEALDH1A1KDM4EHPGD | |
| SCHEMBL8099495 | 0.81 | MAPT (0.45) | ALDH1A1KDM4EMEN1KMT2AHRH2 | |
| SCHEMBL8108969 | 0.80 | TSHR (0.44) | ELANEALDH1A1KDM4EHPGDHTT | |
| SCHEMBL19639773 | 0.72 | ELANE (0.53) | ELANE | |
| SCHEMBL19639807 | 0.69 | ELANE (0.48) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778768-A4 | FORMULATIONS AND METHODS FOR PROVIDING PROLONGED LOCAL ANESTHESIA | EURO CELTIQUE SA (LU) | 2000-10-11 | — | — | EP | disclosed |
| EP-0987253-A1 | PYRAZOLONE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5968967-A | INHIBIT PLATELET AGGREGATION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0778768-A1 | FORMULATIONS AND METHODS FOR PROVIDING PROLONGED LOCAL ANESTHESIA | Euroceltique S.A. (LU) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996041616-A1 | FORMULATIONS AND METHODS FOR PROVIDING PROLONGED LOCAL ANESTHESIA | EURO-CELTIQUE, S.A. (LU) | 1996-12-27 | — | — | WO | disclosed |