Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113217 | 0.91 | MAPT (0.45) | TSHRMAPTKMT2ACA1CA2 | |
| SCHEMBL8113306 | 0.81 | ALDH1A1 (0.42) | KMT2ACA1CA2MEN1KDM4E | |
| SCHEMBL8114850 | 0.81 | HRH2 (0.39) | TSHRMAPTKMT2AMEN1FPR2 | |
| SCHEMBL8099596 | 0.80 | NPEPPS (0.39) | MAPTKMT2ACA1CA2MEN1 | |
| SCHEMBL8108274 | 0.79 | KIF11 (0.41) | MAPTKMT2AMEN1FPR2KDM4E | |
| SCHEMBL8099495 | 0.79 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Ethyl Benzoate SCHEMBL28451031 | 0.71 | KMT2A (0.56) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24157593 | 0.70 | ALDH1A1 (0.49) | TSHRMAPTKMT2AMEN1KDM4E | |
| SCHEMBL6464539 | 0.68 | ALDH1A1 (0.58) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10313589 | 0.68 | ALDH1A1 (0.48) | TSHRMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987253-A1 | PYRAZOLONE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5968967-A | INHIBIT PLATELET AGGREGATION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |