Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647671 | 0.81 | — | — | |
| SCHEMBL9647187 | 0.80 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL8099224 | 0.79 | KDM4E (0.35) | TSHR | |
| SCHEMBL8107056 | 0.78 | — | — | |
| SCHEMBL9519037 | 0.78 | KDM4E (0.38) | — | |
| SCHEMBL8096496 | 0.77 | — | — | |
| SCHEMBL10556915 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2TSHR | |
| SCHEMBL8089757 | 0.76 | — | — | |
| SCHEMBL8105465 | 0.76 | PARP1 (0.35) | TSHR | |
| SCHEMBL10855944 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626372-B1 | 2-hydroxy-3-[1-(1H-imidazol-4-yl)alkyl]benzenecarboximid-amides for the treatment of glaucoma | UCB SA (BE) | 2000-12-20 | — | — | EP | disclosed |