Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094986 | 0.96 | LPL (0.49) | MTNR1AMTNR1BLPLLIPGSKP2 | |
| SCHEMBL8094151 | 0.94 | LPL (0.53) | MTNR1AMTNR1BLPLLIPG | |
| SCHEMBL8095725 | 0.93 | LPL (0.54) | MTNR1AMTNR1BLPLLIPG | |
| SCHEMBL8093587 | 0.93 | LPL (0.54) | MTNR1AMTNR1BLPLLIPG | |
| SCHEMBL8096294 | 0.93 | LPL (0.54) | MTNR1AMTNR1BLPLLIPG | |
| SCHEMBL10106221 | 0.92 | LPL (0.54) | MTNR1AMTNR1BCALM1LPLLIPG | |
| SCHEMBL5433566 | 0.92 | LPL (0.52) | MTNR1AMTNR1BLPLLIPGSKP2 | |
| SCHEMBL4077078 | 0.91 | LPL (0.56) | MTNR1AMTNR1BLPLLIPGDRD2 | |
| SCHEMBL8095304 | 0.90 | LPL (0.56) | LPLLIPG | |
| SCHEMBL8085699 | 0.89 | LPL (0.57) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |