Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.53 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095725 | 0.98 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8093587 | 0.98 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8096294 | 0.98 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL10106221 | 0.98 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL4077078 | 0.96 | LPL (0.56) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8095304 | 0.96 | LPL (0.56) | LPLLIPGPPARGPPARAGPR3 | |
| SCHEMBL8099752 | 0.94 | MTNR1A (0.51) | LPLLIPGMTNR1AMTNR1B | |
| SCHEMBL8085699 | 0.94 | LPL (0.57) | LPLLIPGPPARGPPARAGPR3 | |
| SCHEMBL8095321 | 0.94 | LPL (0.57) | LPLLIPGPPARGPPARAGPR3 | |
| SCHEMBL8094550 | 0.94 | LPL (0.57) | LPLLIPGPPARGPPARAGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |