Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094151 | 0.98 | LPL (0.53) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL4077078 | 0.98 | LPL (0.56) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8095725 | 0.96 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8093587 | 0.96 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8096294 | 0.96 | LPL (0.54) | LPLLIPGMTNR1AMTNR1BKCNH2 | |
| SCHEMBL8095304 | 0.94 | LPL (0.56) | LPLLIPGPPARGPPARATDP1 | |
| SCHEMBL8098362 | 0.94 | LPL (0.59) | LPLLIPGKCNH2PPARGPPARA | |
| SCHEMBL8099752 | 0.92 | MTNR1A (0.51) | LPLLIPGMTNR1AMTNR1BDRD2 | |
| SCHEMBL8085699 | 0.92 | LPL (0.57) | LPLLIPGPPARGPPARA | |
| SCHEMBL8095321 | 0.92 | LPL (0.57) | LPLLIPGPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | CUTA, MMP8, CLPP | LPL 1000/4885LIPG 1070/4885MTNR1A 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.