SCHEMBL810011

SCHEMBL810011

CC(=O)CCCCCOc1ccc(OCC(=O)O)cc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 4/20 0.52
CYSLTR1 Q9Y271 4/20 0.52
PPARD Q03181 2/20 0.48
PTPN11 Q06124 6/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
S1PR3 Q99500 1/20 0.46
PLA2G4B P0C869 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
TSHR P16473 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
NFKB1 P19838 1/20 0.44
PPARG P37231 1/20 0.44
BLM P54132 1/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810001 0.90 CYSLTR2 (0.43) CYSLTR2CYSLTR1PPARDPTPN11PTPN1
SCHEMBL13418164 0.83 PTGDR2 (0.47) CYSLTR2CYSLTR1PPARDPTGDR2TSHR
SCHEMBL809958 0.82 PLA2G4B (0.56) PPARDPLA2G4B
SCHEMBL8528987 0.82 PTGDR2 (0.55) PPARDPTGDR2TSHRLMNAMAPT
SCHEMBL809926 0.80 ALDH1A1 (0.50) CYSLTR2CYSLTR1PPARDPTGDR2TSHR
SCHEMBL25788077 0.78 PTPN11 (0.67) PTPN11PTPN1PTPN6S1PR3PLA2G4B
SCHEMBL9417624 0.78 PTPN11 (0.67) PTPN11PTPN1PTPN6S1PR3PLA2G4B
SCHEMBL35211213 0.76 PTPN11 (0.64) PTPN11PTPN1PTPN6S1PR3PLA2G4B
SCHEMBL16190196 0.76 PTPN11 (0.59) PTPN11PTPN1PTPN6S1PR3PLA2G4B
SCHEMBL4147094 0.75 KDM4E (0.59) PPARDPTGDR2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD CYSLTR2 3949/4885CYSLTR1 3677/4885PPARD 626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.