Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107428 | 0.85 | XDH (0.46) | XDHTDP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7765911 | 0.83 | XDH (0.55) | XDHTDP1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL22441922 | 0.80 | POLB (0.60) | XDHTDP1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL15028056 | 0.80 | NR1H4 (0.53) | XDHTDP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8844738 | 0.80 | CA12 (0.57) | XDHTDP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22441920 | 0.80 | POLB (0.60) | XDHTDP1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL22447135 | 0.79 | XDH (0.51) | XDHTDP1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL2723179 | 0.79 | ALDH1A1 (0.57) | XDHTDP1SMN1; SMN2RAB9ANPC1 | |
| Dimethyl Phthalate SCHEMBL28487305 | 0.77 | TDP1 (0.65) | XDHTDP1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL19041838 | 0.77 | XDH (0.52) | XDHTDP1SMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007300-A2 | SUBSTITUTED AMINO-QUINAZOLINONES, MEDICAMENTS COMPRISING SAID COMPOUND, THEIR USE AND THEIR METHOD OF MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |