SCHEMBL8100119

SCHEMBL8100119

CN(C)C(=[O+]ON1C(=O)c2ccccc2C1=O)N(C)C.F[B-](F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.38
MEN1 O00255 3/20 0.38
VDR P11473 2/20 0.38
ALDH1A1 P00352 7/20 0.37
MAPT P10636 5/20 0.37
KDM4E B2RXH2 4/20 0.37
HPGD P15428 3/20 0.37
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 1/20 0.35
F2 P00734 2/20 0.35
CYP3A4 P08684 1/20 0.33
XBP1 P17861 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
POLB P06746 1/20 0.32
RPS6KA2 Q15349 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8102289 0.92 VDR (0.41) KMT2AMEN1VDRALDH1A1MAPT
Perchlorate SCHEMBL8095660 0.88 VDR (0.41) KMT2AMEN1VDRALDH1A1MAPT
SCHEMBL8093995 0.74
SCHEMBL16858647 0.73 GAA (0.36) KMT2AMEN1VDRALDH1A1MAPT
SCHEMBL8099998 0.71 GAA (0.35) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL6496871 0.68 KMT2A (0.42) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL2828593 0.67 GAA (0.42) KMT2AMEN1VDRALDH1A1MAPT
SCHEMBL6496874 0.67 ERCC1 (0.41) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL1674865 0.66 NPSR1 (0.41) KMT2AALDH1A1MAPTKDM4EHPGD
Perchlorate SCHEMBL8099613 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061904-A1 NANOPARTICLES, METHOD FOR PRODUCING NANOPARTICLES AND USE OF THE SAME Aventis Research & Technologies GmbH & Co KG (DE) 2000-12-27 EP disclosed
WO-1999047130-A1 NANOPARTICLES, METHOD FOR PRODUCING NANOPARTICLES AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-09-23 WO disclosed