SCHEMBL2828593

SCHEMBL2828593

CN(C)C(=S)ON1C(=O)c2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
ALDH1A1 P00352 7/20 0.40
CYP1A2 P05177 3/20 0.40
VDR P11473 1/20 0.40
CYP2C9 P11712 1/20 0.40
MAPT P10636 5/20 0.40
HPGD P15428 4/20 0.40
KMT2A Q03164 4/20 0.40
KDM4E B2RXH2 3/20 0.40
PLIN1 O60240 1/20 0.38
ALOX15 P16050 1/20 0.38
PLIN5 Q00G26 1/20 0.38
ABHD5 Q8WTS1 1/20 0.38
MEN1 O00255 3/20 0.37
CYP3A4 P08684 1/20 0.37
XBP1 P17861 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
F2 P00734 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13291123 0.85 ALDH1A1 (0.50) ALDH1A1CYP1A2MAPTHPGDKMT2A
SCHEMBL2827279 0.83 CASP3 (0.44) GAAALDH1A1CYP1A2VDRMAPT
SCHEMBL13327154 0.81 GAA (0.44) GAAALDH1A1CYP1A2VDRCYP2C9
SCHEMBL22634042 0.77 CYP1A2 (0.45) GAAALDH1A1CYP1A2VDRCYP2C9
SCHEMBL2828765 0.76
SCHEMBL2827666 0.75 SPHK1 (0.41) GAAALDH1A1MAPTHPGDKMT2A
SCHEMBL29838651 0.75 ALDH1A1 (0.47) GAAALDH1A1CYP1A2VDRCYP2C9
SCHEMBL859822 0.75 ALDH1A1 (0.47) GAAALDH1A1CYP1A2VDRCYP2C9
SCHEMBL2177419 0.74 ALDH1A1 (0.50) GAAALDH1A1CYP1A2VDRCYP2C9
SCHEMBL426217 0.74 ALDH1A1 (0.50) GAAALDH1A1CYP1A2VDRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101056893-B N-substituted imides as polymerization initiators CIBA SC HOLDING AG 2011-06-08 CN disclosed
EP-1828258-B1 N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS BASF SE (DE) 2010-06-30 EP disclosed
EP-1828258-B1 N-SUBSTITUTED IMIDES AS POLYMERIZATION INITIATORS BASF SE (DE) 2010-06-30 EP disclosed
US-7723399-B2 N-substituted imides as polymerization initiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723399-B2 N-substituted imides as polymerization initiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723399-B2 N-substituted imides as polymerization initiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20080132600-A1 N-Substituted Imides As Polymerization Initiators CIBA SPECIALTY CHEMICALS CORP. 2008-06-05 US disclosed
US-20080132600-A1 N-Substituted Imides As Polymerization Initiators CIBA SPECIALTY CHEMICALS CORP. 2008-06-05 US disclosed
US-20080132600-A1 N-Substituted Imides As Polymerization Initiators CIBA SPECIALTY CHEMICALS CORP. 2008-06-05 US disclosed
CN-101056893-A N-substituted imides as polymerization initiators CIBA SC HOLDING AG (CH) 2007-10-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132600-A1 N-Substituted Imides As Polymerization Initiators NR1H3, SIGMAR1, NR1H2 GAA 4880/4885ALDH1A1 2799/4885CYP1A2 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.