SCHEMBL8100149

SCHEMBL8100149

CC(N)(/C=C\c1ccccc1P(c1ccccc1)c1ccccc1)/C=C\c1ccccc1P(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
DRD1 P21728 2/20 0.34
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8104253 0.79 CYP2C19 (0.32) CYP2C19
SCHEMBL13908972 0.77 CYP3A4 (0.42) CYP3A4TDP1DRD1
SCHEMBL503707 0.72 CYP3A4 (0.46) CYP3A4TDP1DRD1
SCHEMBL29809925 0.72 CYP3A4 (0.46) CYP3A4TDP1DRD1
SCHEMBL27880843 0.72 CYP3A4 (0.41) CYP3A4TDP1DRD1
SCHEMBL13908975 0.71 NFE2L2 (0.54) CYP3A4TDP1CYP2C19
SCHEMBL13091168 0.70 LMNA (0.30) DRD1
SCHEMBL2850053 0.69 TDP1 (0.42) CYP3A4TDP1DRD1
SCHEMBL28176536 0.69 CYP3A4 (0.42) CYP3A4TDP1DRD1
SCHEMBL13908991 0.69 ALOX5 (0.45) CYP3A4TDP1DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103867-A METAL COMPLEX MIXED WITH LEWIS AND/OR PROTIC ACIDS; SIMPLIFICATION, EFFICIENCY, HALOGEN-FREE STARTING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-08-15 US disclosed