Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895439 | 0.86 | TAS1R3 (0.48) | ATMKMT2ATSHRALDH1A1TAS1R3 | |
| SCHEMBL8729661 | 0.82 | ATM (0.39) | ATMKMT2ATSHRALDH1A1LMNA | |
| SCHEMBL9015106 | 0.82 | TSHR (0.61) | KMT2AKMOTSHRPOLBHPGD | |
| SCHEMBL19806639 | 0.81 | ERCC5 (0.55) | KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL7582286 | 0.80 | HPGD (0.40) | ATMKMT2AALDH1A1LMNAAGTR1 | |
| SCHEMBL4243119 | 0.79 | KMT2A (0.40) | ATMKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL6678525 | 0.77 | KMO (0.59) | ATMKMT2AKMOTSHRHPGD | |
| SCHEMBL8525016 | 0.76 | TDP1 (0.39) | ATMKMT2AALDH1A1SLC6A4HPGD | |
| SCHEMBL13308382 | 0.76 | KMO (0.50) | KMOTSHRALDH1A1LMNAAGTR1 | |
| SCHEMBL2127069 | 0.74 | TSHR (0.57) | KMOTSHRSLC6A4SLC6A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |