Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729661 | 0.81 | ATM (0.39) | HPGDATMHDAC3HDAC4HDAC1 | |
| SCHEMBL4243119 | 0.81 | KMT2A (0.40) | HPGDPOLBATMALDH1A1LMNA | |
| SCHEMBL8100211 | 0.80 | ATM (0.51) | HPGDPOLBATMALDH1A1LMNA | |
| SCHEMBL7578086 | 0.75 | ALDH1A1 (0.51) | HPGDATMALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8724610 | 0.74 | ERCC5 (0.38) | HPGDALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL17895439 | 0.73 | TAS1R3 (0.48) | ATMALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8726663 | 0.72 | HPGD (0.38) | HPGDPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7574482 | 0.72 | HPGD (0.33) | HPGDPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8724282 | 0.72 | KMT2A (0.33) | HPGDLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19806639 | 0.72 | ERCC5 (0.55) | POLBALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |