Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095742 | 0.88 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8100796 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL8095044 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL8092716 | 0.82 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL8419785 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8421023 | 0.76 | LMNA (0.48) | PTGS2PTGS1 | |
| SCHEMBL8086584 | 0.76 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8099203 | 0.75 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL8086507 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL6725750 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |