Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100751 | 0.88 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8086584 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8099203 | 0.86 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6725750 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL21561303 | 0.79 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL27430932 | 0.79 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6725509 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8086517 | 0.78 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL8549849 | 0.77 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL7841871 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |