SCHEMBL8100780

SCHEMBL8100780

CCCCCCCCCCCCOc1ccc(S(=O)(=O)Nc2cccc(C(N)=O)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.60
ATIC P31939 1/20 0.58
LMNA P02545 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HTT P42858 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
TCF4 P15884 2/20 0.54
CTNNB1 P35222 2/20 0.54
NR1H4 Q96RI1 2/20 0.54
FABP1 P07148 1/20 0.52
MAPT P10636 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
XBP1 P17861 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8100775 0.89 WDR5 (0.60) WDR5LMNASMN1; SMN2HTTCYP1A2
SCHEMBL7181360 0.84 SMN1; SMN2 (0.59) WDR5LMNASMN1; SMN2HTTCYP1A2
SCHEMBL8757054 0.84 SMN1; SMN2 (0.59) WDR5LMNASMN1; SMN2HTTCYP1A2
SCHEMBL7177706 0.83 SMN1; SMN2 (0.60) WDR5LMNASMN1; SMN2HTTCYP1A2
SCHEMBL3554315 0.81 WDR5 (0.64) WDR5LMNASMN1; SMN2HTTCYP1A2
SCHEMBL16430799 0.81 TCF4 (0.52) WDR5HTTTCF4CTNNB1NR1H4
SCHEMBL787919 0.80 WDR5 (0.72) WDR5NR1H4FABP1MAPTTDP1
SCHEMBL7170774 0.80 SMN1; SMN2 (0.62) WDR5LMNASMN1; SMN2HTTCYP1A2
SCHEMBL31681342 0.79 ATIC (0.62) WDR5ATICLMNASMN1; SMN2TCF4
SCHEMBL16430707 0.78 TCF4 (0.54) WDR5LMNASMN1; SMN2HTTTCF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156489-A Silver halide photosensitive material KONICA CORPORATION (JP) 2000-12-05 US disclosed
EP-0651289-B1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK CO (US) 1999-08-11 EP disclosed
US-5641613-A SUPPORT BEARING LIGHT SENSITIVE SILVER HALIDE LAYER CONTAINING BICYCLIC AZOLE COUPLER, AZOPYRAZOLONE MASKING COUPLER, LOW IMPACT DEVELOPMENT INHIBITOR RELEASING COUPLER EASTMAN KODAK COMPANY (US) 1997-06-24 US disclosed
EP-0646840-B1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK CO (US) 1997-01-29 EP disclosed
US-5591569-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1997-01-07 US disclosed
US-5482821-A Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1996-01-09 US disclosed
US-5466568-A Multilayer light sensitive photographic film EASTMAN KODAK COMPANY (US) 1995-11-14 US disclosed
EP-0651289-A1 Photographic element containing an azopyrazolone masking coupler exhibiting reduced fogging EASTMAN KODAK COMPANY (US) 1995-05-03 EP disclosed
EP-0646841-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0646840-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0646842-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0232101-B1 Light-sensitive silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1994-03-23 EP disclosed
US-4992357-A Stability, adhesion resistant KONICA CORPORATION (JP) 1991-02-12 US disclosed
EP-0350022-A2 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1990-01-10 EP disclosed