Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 16/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314997 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL7505035 | 0.86 | PTGS2 (0.57) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL6315415 | 0.86 | PTGS2 (0.50) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL6315584 | 0.86 | PTGS2 (0.51) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL5732493 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL6310274 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL6314518 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL8549844 | 0.84 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6310821 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL6308549 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1CDK2ABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | claimed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | claimed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |