SCHEMBL810081

SCHEMBL810081

CCCC(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809819 0.83 FAAH (0.86)
SCHEMBL463411 0.81 FAAH (1.00)
SCHEMBL11533523 0.81 FAAH (0.57)
SCHEMBL14304568 0.80
SCHEMBL2819894 0.79 FAAH (1.00)
SCHEMBL31152148 0.79 FAAH (1.00)
SCHEMBL6314290 0.79 FAAH (0.52)
SCHEMBL10966855 0.79 FAAH (1.00)
SCHEMBL28471077 0.79 FAAH (1.00)
SCHEMBL4653611 0.79 FAAH (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110028438-B Synthetic method of 3-phenyl-3-indole trifluoromethyl propyl ketone derivative 浙江农林大学暨阳学院 2022-07-12 CN claimed
WO-2007121851-A1 LIGHTENING AND/OR COLOURING AGENTS COMPRISING HALOGENATED KETONES HENKEL AG & CO. KGAA (DE) 2007-11-01 WO claimed
EP-1420771-A2 USE OF TRIFLUOROACETYL ALKYL-SUBSTITUTED PHENYL DERIVATIVES, PHENOL DERIVATIVES, AND BENZOYL DERIVATIVES IN THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY AND ACCOMPANYING DISEASES AND/OR SECONDARY DISEASES Solvay Pharmaceuticals GmbH (DE) 2004-05-26 EP claimed
WO-2003007923-A2 USE OF TRIFLUOROACETYL ALKYL-SUBSTITUTED PHENYL DERIVATIVES, PHENOL DERIVATIVES, AND BENZOYL DERIVATIVES IN THE TREATMENT AND/OR PROPHYLAXIS OF OBESITY AND ACCOMPANYING DISEASES AND/OR SECONDARY DISEASES SOLVAY PHARMACEUTICALS GMBH (DE) 2003-01-30 WO claimed
JP-60058082-A None JP disclosed
JP-6113867-A None JP disclosed
US-12612407-B2 Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist BEONE MEDICINES I GMBH (CH) 2026-04-28 US disclosed
US-20250343048-A1 ETCHING METHOD RESONAC CORPORATION (JP) 2025-11-06 US disclosed
CN-118562175-B Block all-carbon-connected proton exchange membrane and preparation method and application thereof 佛山大学 2025-04-01 CN disclosed
EP-4481794-A1 ETCHING METHOD Resonac Corporation (JP) 2024-12-25 EP disclosed
CN-118679554-A Etching method 株式会社力森诺科 2024-09-20 CN disclosed
CN-118562175-A Block all-carbon-connected proton exchange membrane and preparation method and application thereof 佛山科学技术学院 2024-08-30 CN disclosed
US-7335897-B2 Method and system for desorption electrospray ionization PURDUE RESEARCH FOUNDATION (US) 2008-02-26 US disclosed
WO-2007121851-A1 LIGHTENING AND/OR COLOURING AGENTS COMPRISING HALOGENATED KETONES HENKEL AG & CO. KGAA (DE) 2007-11-01 WO disclosed
EP-0944618-A1 NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE FOURNIER INDUSTRIE ET SANTE (FR) 1999-09-29 EP disclosed
WO-1998024783-A1 NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE FOURNIER INDUSTRIE ET SANTE (FR) 1998-06-11 WO disclosed
JP-H06113867-A PRODUCTION OF 1,1,1-TRIFLUORO-2-ALKANOL JAPAN ENERGY CORP 1994-04-26 JP disclosed
US-4855460-A ZINC OR CADMIUM CATALYST RHONE-POULENC CHIMIE (FR) 1989-08-08 US disclosed
JP-S6058082-A PRODUCTION OF FLUORINE-CONTAINING CARBONYL COMPOUND DAIKIN IND LTD 1985-04-04 JP disclosed
JP-S0658082-A 0001-01-01 JP disclosed