Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 12/20 | 0.33 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16995784 | 0.75 | BACE1 (0.38) | LMNAMAPTHTTBLMBACE1 | |
| SCHEMBL28922769 | 0.72 | BACE1 (0.38) | LMNAMAPTHTTBLMBACE1 | |
| SCHEMBL30148835 | 0.72 | BACE1 (0.41) | LMNAMAPTHTTBLMBACE1 | |
| SCHEMBL30148868 | 0.72 | BACE1 (0.38) | LMNAMAPTHTTBLMBACE1 | |
| SCHEMBL1758994 | 0.72 | LMNA (0.40) | LMNAMAPTHTTBLMBACE1 | |
| SCHEMBL8111934 | 0.71 | CTNNB1 (0.41) | MAPTMEN1ALDH1A1POLBHPGD | |
| SCHEMBL7920247 | 0.69 | BACE1 (0.35) | LMNAMAPTHTTBLMBACE1 | |
| SCHEMBL7911081 | 0.68 | BACE1 (0.51) | BACE1 | |
| SCHEMBL155111 | 0.67 | MAPT (0.53) | LMNAMAPTHTTBLMAHR | |
| SCHEMBL29584634 | 0.67 | MAPT (0.53) | LMNAMAPTHTTBLMAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |