Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584634 | 1.00 | MAPT (0.53) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL7839082 | 0.98 | MAPT (0.52) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL4854354 | 0.88 | LMNA (0.50) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL3520162 | 0.86 | LMNA (0.48) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL267355 | 0.83 | LMNA (0.53) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL30640621 | 0.80 | DYRK1A (0.54) | MAPTPRKCIDYRK1ADYRK2DYRK1B | |
| SCHEMBL8187712 | 0.80 | DYRK1A (0.54) | MAPTPRKCIDYRK1ADYRK2DYRK1B | |
| SCHEMBL2177890 | 0.79 | LMNA (0.41) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL23188919 | 0.79 | DYRK1A (0.40) | MAPTLMNAHTTBLMPRKCI | |
| SCHEMBL6587136 | 0.79 | DYRK1A (0.46) | MAPTLMNAHTTBLMPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452201-B | Synthetic method of benzofuran heterocyclic sulfonyl chloride | 泰州职业技术学院 | 2022-09-23 | — | — | CN | claimed |
| CN-104370865-A | Method for synthesizing 3-(2,3-dihydrobenzofuran-5-yl) propionic acid through Heck reaction | SUZHOU JONATHAN NEW MATERIALS TECHNOLOGY CO LTD | 2015-02-25 | — | — | CN | claimed |
| CN-101279963-A | Preparation of darifenacin intermediate 5-(halogenated ethyl)-2,3-dihydrobenzofuran | BEIJING CHEMSUN PHARMACEUTICAL (CN) | 2008-10-08 | — | — | CN | claimed |
| EP-4720037-A1 | CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | 16380026 Canada Inc. (CA) | 2026-04-08 | — | — | EP | disclosed |
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| EP-4694889-A1 | COMPOUNDS AND METHODS FOR TREATING PROTEIN AGGREGATION DISEASES | Acelot, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4626870-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | University of Copenhagen (DK) | 2025-10-08 | — | — | EP | disclosed |
| US-12398097-B2 | WDR5-MYC inhibitors | VANDERBILT UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| US-12365655-B2 | Compounds | CTXT PTY LTD (AU) | 2025-07-22 | — | — | US | disclosed |
| EP-4584259-A1 | CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS | Innovo Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| US-20250221979-A1 | NOVEL HETEROCYCLIC COMPOUND | SHOUYAO HOLDINGS BEIJING CO LTD (CN) | 2025-07-10 | — | — | US | disclosed |
| US-6043247-A | A SUBSTITUTED ACRYLIC ACIDS FOR USE IN TREATMENT OF HUMAN AND ANIMAL DISORDERS, AND PURIFICATION OF PROTEINS OR GLYCOPROTEINS, AND TO THEIR USE IN DIAGNOSIS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | disclosed |
| WO-1999043657-A1 | 2-ARYLETHYL-(PIPERIDIN-4-YLMETHYL)AMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-02 | — | — | WO | disclosed |
| WO-1997039748-A1 | MODULATORS OF MOLECULES WITH PHOSPHOTYROSINE RECOGNITION UNITS | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |
| EP-0482108-B1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF | NOVO NORDISK AS (DK) | 1996-03-20 | — | — | EP | disclosed |
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| US-5262430-A | Antidiabetic agent lowers blood glucose in mammals in type 2 non insulin dependent diabetes | NOVO NORDISK A/S (DK) | 1993-11-16 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0482108-A1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF. | NOVO NORDISK AS (DK) | 1992-04-29 | — | — | EP | disclosed |
| WO-1991000862-A1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF | NOVO NORDISK A/S (DK) | 1991-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062393-A1 | Compounds | SCN2B, ABCB11, SCN1B | MAPT 2629/4885LMNA 3274/4885HTT 941/4885 |
| US-20250221979-A1 | NOVEL HETEROCYCLIC COMPOUND | MAPT, MNAT1, MAT2A | MAPT 1/4885LMNA 876/4885HTT 17/4885 |
| US-12398097-B2 | WDR5-MYC inhibitors | MYC, WDR5, MYCBP | MAPT 1222/4885LMNA 2680/4885HTT 1364/4885 |
| US-12365655-B2 | Compounds | SLC10A1, ABCB11, PCSK9 | MAPT 1136/4885LMNA 1392/4885HTT 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.