Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103580 | 0.92 | NPY5R (0.56) | NPY5RNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8109468 | 0.92 | SAE1 (0.44) | NPY5RTSHRMEN1KMT2APOLB | |
| SCHEMBL7609572 | 0.92 | RAB9A (0.53) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1573640 | 0.91 | MEN1 (0.54) | NPY5RTSHRMEN1KMT2ANPSR1 | |
| SCHEMBL7612777 | 0.89 | SLC1A3 (0.49) | NPY5RMEN1KMT2ANPC1TP53 | |
| SCHEMBL7609578 | 0.89 | NOX1 (0.48) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7613037 | 0.86 | NPY5R (0.65) | NPY5RNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7611231 | 0.86 | GAA (0.64) | MEN1KMT2ANPSR1NPC1POLB | |
| SCHEMBL7615446 | 0.86 | SLC1A3 (0.51) | NPY5RMEN1KMT2ANPSR1CA1 | |
| SCHEMBL7615411 | 0.86 | SMN1; SMN2 (0.61) | NPY5RMEN1KMT2ANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121323-A | LIPOXYGENASE INHIBITOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | disclosed |