Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613037 | 0.94 | NPY5R (0.65) | NPY5RALDH1A1HPGDNPC1CRHBP | |
| SCHEMBL8101940 | 0.92 | NPY5R (0.44) | NPY5RGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8109468 | 0.84 | SAE1 (0.44) | NPY5RHPGDCRHBPCRHR2 | |
| SCHEMBL7609572 | 0.84 | RAB9A (0.53) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL1573640 | 0.83 | MEN1 (0.54) | NPY5RALDH1A1GAANPC1RAB9A | |
| SCHEMBL7610162 | 0.82 | RAB9A (0.60) | NPY5RALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7612429 | 0.82 | MITF (0.56) | NPY5RALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7609578 | 0.81 | NOX1 (0.48) | ALDH1A1NPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL7612777 | 0.81 | SLC1A3 (0.49) | NPY5RALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7610722 | 0.80 | RARB (0.52) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | claimed |
| US-6121323-A | LIPOXYGENASE INHIBITOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | disclosed |