Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615446 | 0.94 | SLC1A3 (0.51) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8101940 | 0.92 | NPY5R (0.44) | TSHRPOLBMEN1KMT2ANPY5R | |
| SCHEMBL7609572 | 0.84 | RAB9A (0.53) | TSHRMEN1KMT2AHPGDMAPT | |
| SCHEMBL8103580 | 0.84 | NPY5R (0.56) | HPGDNPY5RCRHBPCRHR2 | |
| SCHEMBL1573640 | 0.83 | MEN1 (0.54) | TSHRMEN1KMT2AMAPTNPY5R | |
| SCHEMBL8107929 | 0.83 | SAE1 (0.46) | SAE1UBA2TSHRPOLBMEN1 | |
| SCHEMBL7612777 | 0.81 | SLC1A3 (0.49) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7609578 | 0.81 | NOX1 (0.48) | MEN1LMNAKMT2AMAPT | |
| SCHEMBL7613037 | 0.79 | NPY5R (0.65) | HPGDNPY5RCRHBPCRHR2 | |
| SCHEMBL7611231 | 0.79 | GAA (0.64) | POLBMEN1LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | claimed |
| US-6121323-A | LIPOXYGENASE INHIBITOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | disclosed |