Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386633 | 0.89 | MAPT (0.46) | MAPTALDH1A1MAOBMAOASMN1; SMN2 | |
| SCHEMBL811151 | 0.82 | MAPT (0.48) | MAPTALDH1A1MAOBMAOASMN1; SMN2 | |
| SCHEMBL4973845 | 0.82 | SIRT2 (0.41) | MAOBMAOASIRT2FFAR1FFAR4 | |
| SCHEMBL811413 | 0.78 | PDE7A (0.48) | MAPTALDH1A1MAOBMAOAPDE7A | |
| SCHEMBL5067776 | 0.78 | PDE7A (0.53) | MAPTALDH1A1SMN1; SMN2PDE7APDE7B | |
| SCHEMBL4976601 | 0.77 | GPR84 (0.46) | MAPTMAOBMAOASIRT2SMN1; SMN2 | |
| SCHEMBL2961961 | 0.77 | MAPT (0.51) | MAPTALDH1A1MAOBMAOASMN1; SMN2 | |
| SCHEMBL810343 | 0.76 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2PDE7APDE7B | |
| SCHEMBL8992675 | 0.76 | FFAR1 (0.52) | MAOBMAOASIRT2FFAR1FFAR4 | |
| SCHEMBL810228 | 0.76 | HTT (0.44) | MAPTALDH1A1SMN1; SMN2PDE7APDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |