Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249364 | 0.96 | HTR2A (0.63) | HTR2ACALM1LMNABCL2BCL2L1 | |
| SCHEMBL8086620 | 0.94 | HTR2A (0.54) | HTR2ACALM1LTA4HSLC6A2SLC6A4 | |
| SCHEMBL8093734 | 0.88 | HTR2A (0.55) | HTR2ACALM1LTA4HLMNABCL2 | |
| SCHEMBL8771537 | 0.86 | HTR2A (0.53) | HTR2ALTA4HSLC6A2SLC6A4SLC6A3 | |
| Isopropylamine SCHEMBL27701434 | 0.86 | HTR2A (0.58) | HTR2ACALM1BCL2BCL2L1SLC6A2 | |
| SCHEMBL8095678 | 0.86 | CALM1 (0.44) | HTR2ACALM1LTA4HLMNABCL2 | |
| SCHEMBL8093182 | 0.86 | HTR2A (0.53) | HTR2ACALM1LMNABCL2L1HTT | |
| SCHEMBL8101085 | 0.86 | LTA4H (0.47) | HTR2ALTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6546751 | 0.86 | HTR2A (0.47) | HTR2ALTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8094124 | 0.85 | HTR2A (0.52) | HTR2ALMNABCL2L1TP53SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |