Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970753 | 0.82 | HRH3 (0.58) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL24164418 | 0.79 | TAAR1 (0.59) | HRH3TAAR1BPTF | |
| SCHEMBL659509 | 0.78 | HRH3 (0.82) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL7258875 | 0.76 | ALDH1A1 (0.47) | HRH3ALDH1A1TSHRTAAR1NOS1 | |
| SCHEMBL6317620 | 0.76 | HRH3 (0.47) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL2688970 | 0.76 | HRH3 (0.56) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL26735733 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TAAR1POLB | |
| SCHEMBL15219075 | 0.74 | HRH3 (0.54) | HRH3ALDH1A1TSHRTAAR1LSS | |
| Hydrochloric Acid SCHEMBL1118029 | 0.74 | HRH3 (0.54) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL28247922 | 0.74 | LSS (0.46) | HRH3ALDH1A1TSHRTAAR1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087369-A | AN IMMUNOSUPPRESSIVE AGENT, ANTIALLERGIC AGENT, ANTI-INFLAMMATORY AGENT AND BRAIN CELL-PROTECTING AGENT | TORAY INDUSTRIES, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |