R-Chloropropionate

R-Chloropropionate

SCHEMBL8102515

C=Cc1ccncc1.O=C(O)CCCl.[NaH]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.40
JUN P05412 1/20 0.38
NFKB1 P19838 1/20 0.38
KDM4E B2RXH2 4/20 0.37
KMT2A Q03164 3/20 0.37
HTT P42858 2/20 0.37
FFAR1 O14842 1/20 0.37
SNCA P37840 1/20 0.37
MAPT P10636 4/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.34
NAPRT Q6XQN6 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL11408290 0.79 JUN (0.42) BCHEJUNNFKB1KDM4EKMT2A
Hydrogen Peroxide SCHEMBL27481776 0.78 ALDH1A1 (0.53) JUNNFKB1KDM4EKMT2ASNCA
SCHEMBL28627280 0.76 JUN (0.47) JUNNFKB1KDM4EKMT2ASNCA
Acrylic Acid SCHEMBL7781248 0.76 JUN (0.47) JUNNFKB1KDM4EKMT2ASNCA
Acetic Acid SCHEMBL8516899 0.76 JUN (0.47) JUNNFKB1KDM4EKMT2AHTT
Betaine SCHEMBL7997038 0.74 CYP1A2 (0.45) JUNNFKB1SNCASMN1; SMN2ALDH1A1
Malic Acid SCHEMBL28826571 0.73 SMN1; SMN2 (0.50) BCHEJUNNFKB1SNCASMN1; SMN2
Benzene SCHEMBL28291559 0.73 ALDH1A1 (0.60) JUNNFKB1KDM4EKMT2AMAPT
Benzene SCHEMBL28593769 0.73 ALDH1A1 (0.60) JUNNFKB1KDM4EKMT2AMAPT
SCHEMBL11145494 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103831-A POLY(VINYLPYRIDINE BETAINES) CONTAINING A QUATERNARY NITROGEN AND A CARBOXYLATE SALT; EFFECTIVE DYE TRANSFER INHIBITOR PROPERTIES FOR USE, FOR EXAMPLE, IN LAUNDRY DETERGENT AND FABRIC SOFTENER COMPOSITIONS ISP INVESTMENTS INC. (US) 2000-08-15 US claimed