Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972936 | 0.85 | CREBBP (0.41) | CREBBPEP300ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4322060 | 0.79 | MEN1 (0.50) | CREBBPEP300ALDH1A1MEN1KMT2A | |
| SCHEMBL7452571 | 0.77 | ICAM1 (0.44) | CREBBPEP300ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7975649 | 0.76 | MEN1 (0.44) | CREBBPEP300ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8954773 | 0.75 | DHFR (0.35) | HIF1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8370615 | 0.75 | DHFR (0.35) | HIF1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6654536 | 0.74 | TDP1 (0.39) | ALDH1A1KDM4ESMN1; SMN2SLC6A3TDP1 | |
| SCHEMBL8463915 | 0.74 | KDM4E (0.36) | HIF1AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8463919 | 0.74 | KDM4E (0.36) | HIF1AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6721998 | 0.73 | HIF1A (0.46) | HIF1AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1082046-C | Process for producing 2- (2-hydroxymethylphenyl) acetamide derivative and intermediate for production thereof | SHIONOGI & CO (JP) | 2002-04-03 | — | — | CN | disclosed |
| US-6147231-A | Process for producing 2(2-hydroxymethylphenyl)acetamide derivative and intermediate for the production thereof | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0801054-B1 | PROCESS FOR PRODUCING 2-(2-HYDROXYMETHYLPHENYL)ACETAMIDE DERIVATIVE AND INTERMEDIATE FOR THE PRODUCTION THEREOF | SHIONOGI & CO (JP) | 2000-05-24 | — | — | EP | disclosed |
| US-5856573-A | Process for producing 2-(2-hydroxymethylphenyl)acetamide derivative and intermediate for the production thereof | SHIONOGI & CO., LTD (JP) | 1999-01-05 | — | — | US | disclosed |
| CN-1175244-A | Process for producing 2- (2-hydroxymethylphenyl) acetamide derivative and intermediate for production thereof | SHIONOGI & CO (JP) | 1998-03-04 | — | — | CN | disclosed |
| EP-0801054-A1 | PROCESS FOR PRODUCING 2-(2-HYDROXYMETHYLPHENYL)ACETAMIDE DERIVATIVE AND INTERMEDIATE FOR THE PRODUCTION THEREOF | SHIONOGI & CO., LTD. (JP) | 1997-10-15 | — | — | EP | disclosed |