Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155708 | 0.82 | ALDH1A1 (0.45) | NPBWR1MCHR1LMNAALDH1A1TSHR | |
| SCHEMBL6153879 | 0.82 | ALDH1A1 (0.45) | NPBWR1MCHR1LMNAALDH1A1TSHR | |
| SCHEMBL6153923 | 0.80 | ALDH1A1 (0.46) | POLBLMNAALDH1A1TSHRMAPT | |
| SCHEMBL7157105 | 0.80 | CYP1A2 (0.37) | POLBNPBWR1MCHR1LMNAALDH1A1 | |
| SCHEMBL6154647 | 0.79 | NPBWR1 (0.39) | POLBNPBWR1MCHR1APOBEC3GLMNA | |
| SCHEMBL6154006 | 0.78 | AMY1A (0.45) | NPBWR1MCHR1APOBEC3GALDH1A1HPGD | |
| SCHEMBL6154696 | 0.78 | AMY1A (0.45) | NPBWR1MCHR1APOBEC3GALDH1A1HPGD | |
| SCHEMBL6155768 | 0.77 | ALDH1A1 (0.43) | LMNAALDH1A1HTTMAPTHPGD | |
| SCHEMBL6153992 | 0.76 | AMY1A (0.46) | APOBEC3GALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6153864 | 0.75 | POLB (0.38) | POLBLMNAALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046232-A | THERAPEUTICS FOR TREATING AND/OR PREVENTING NEUROLOGICAL, AUTOIMMUNE AND INFLAMMATORY CONDITIONS IN MAMMALS AND AS ANALYTICAL REAGENTS FOR DETECTING FREE RADICALS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-04-04 | — | — | US | disclosed |