Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 10/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 9/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019887 | 0.91 | CES2 (0.40) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7013527 | 0.84 | CES2 (0.37) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2777861 | 0.84 | TAS1R3 (0.39) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18774737 | 0.84 | TAS1R3 (0.33) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11064268 | 0.84 | CES2 (0.42) | CES2CES1ALDH1A1 | |
| SCHEMBL9134506 | 0.81 | CES2 (0.41) | CES2CES1ALDH1A1 | |
| SCHEMBL10587923 | 0.79 | TAS1R3 (0.35) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL20529610 | 0.79 | CES2 (0.50) | CES2CES1ALDH1A1 | |
| SCHEMBL9019898 | 0.78 | TAS1R3 (0.40) | CES2CES1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10631305 | 0.77 | CES2 (0.38) | CES2CES1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565132-B1 | Benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-0823413-A2 | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5591744-A | 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLATE DERIVATIVES; MICROBIOCIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0287951-B1 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5495020-A | CHEMICAL INTERMEDIATE FOR BACTERICIDES, MICROBIOCIDES, DISINFECTANTS; SIDE EFFECT REDUCTION, ABSORPTION | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0565132-A2 | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |